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For many commercially available ELISA’s, the TCL may already provide this service. "Hundreds of distinct ELISA, RIA, enzymatic and HPLC assays are provided. Sysmex XT-2000iV Automated Hematology Analyzer.In addition, user-defined methods may be created and performed on the SIMOA. The SIMOA offers an established menu of analytes that includes cytokines and growth factors. This combination yields detection limits that are nearly 2 two orders of magnitude lower than traditional sandwich ELISAs. This stand alone instrument completely automates the traditional 2-site immunoassay and incorporates a fluorescent tag whose signal is digitized and correlated with concentration of immunoassay target. Siemens Immulite 1000 Immunoassay System.Meso Scale Discovery SECTOR Imager 6000.This instrument automates the 2-site 'sandwich' immunoassay by using combination of magnetic beads and electrochemiluminescent detection to quantify a variety of ligands including hormones, tumor markers, and other proteins and antigens.

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The COBAS e411 is capable of full automated operation and offers a menu of nearly 30 assays that are all FDA certified for use as in-vitro diagnostic procedures. COBAS e411 automated immunochemical analyzer.Assays are all validated as FDA in vitro diagnostic category. More than 80 different biomarkers can be analyzed using a wide spectrum of biochemical assays. Sample types accepted include serum, plasma, urine, CSF and others. This is an automated analyzer capable of executing high throughput analysis on a variety of samples from humans and non humans.

compatibility with the TaqMan® Low Density Array.

continuous wavelength detection from 500-660 nm.

Key applications include gene expression quantitation and the detection of single nucleotide polymorphisms (SNPs) using the fluorogenic 5' nuclease assay." Instrument features: An Automation Accessory combined with 384-well plate capability make the 7900HT system ideally suited to meet the high-throughput requirements of today's drug discovery process. "The 7900HT System is a high-throughput real-time PCR system that detects and quantitates nucleic acid sequences.

ABI PRISM 7900HT sequence detection system.

Institute for Translational Medicine and Therapeutics.

Penn location: first floor Smilow Center for Translational Research CHOP location: 804 Abramson Research Center (ARC) Affiliations: Laboratory testing is integrated across Penn and CHOP, and TCL services are provided at multiple physical locations at both Penn and CHOP. The Translational Core Laboratory consists of the Specimen Collection, Processing and Point of Care, Biochemistry, Cell Culture/DNA Isolation, and Molecular Biology core laboratories. CTRC Translational Core Laboratories (Penn/CHOP)Ĭappola, Anne Rentoumis., MD, ScM Summary: